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This week's selection of the latest in Sickle Cell Disease research features further strides being made towards understanding the complexities of the disease. They range from drug trials to unveiling molecular mechanisms of both SCD and other hemoglobinopathies.
Patient Care
Genomic Counseling in the Newborn Period: Experiences and Views of Genetic Counselors
Research
Molecular mechanisms underlying synergistic adhesion of sickle red blood cells by hypoxia and
low nitric oxide bioavailability
Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension.
Erythro-megakaryocytic transcription factors associated with hereditary anemia.
Ex-Vivo Cytoadherence Phenotypes of Plasmodium falciparum Strains from Malian Children with Hemoglobins A, S, and C
Subchronic Oral Toxicity Study of Decitabine in Combination with Tetrahydrouridine in CD-1 Mice
Methods and Compositions for Treatment of a Genetic Condition (Patent Application Publication)
A phase 2 trial of HQK-1001 in HbE-β thalassemia demonstrates HbF induction and reduced anemia (Letter to the Editor)
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