Saturday, March 22, 2014

This Week In Sickle Cell News

Hello all!

Another week ends with more interesting revelations from the world of Sickle Cell Research. The potential translation of findings into useful clinical practices remains a key goal and driving force behind health sciences research. This week we offer publications relevant to patient care, as well as more basic science research findings related to Sickle Cell Disease and other hemoglobinopathies.


Patient Care


 An update on sickle cell nephropathy

Descriptive approach for sickle cell disease in Eastern of Algeria

The Utility of Routine Electrolytes in Patients with Sickle Cell Anemia Presenting with an Acute Pain Crisis


An Official American Thoracic Society Clinical Practice Guideline: Diagnosis, Risk Stratification, and Management of Pulmonary Hypertension of Sickle Cell Disease


Clinical potential of gene therapy: towards meeting the demand


Reticulocyte parameters: why should clinical laboratories evaluate and report them?



Sickle cell disease in sub-Saharan Africa: stakes and strategies for control of the disease.


Preoperative transfusion in patients with sickle cell disease to prevent perioperative complications: A systematic review and meta-analysis

Pediatric Hematology Providers on Referral for Transplant Evaluation for Sickle Cell Disease: A Regional Perspective



Research


A Short-Term Trial of Butyrate to Stimulate Fetal-Globin-Gene Expression in the ß-Globin Disorders



Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease

Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial Lu/BCAM through phosphodiesterase 4A activation

Excess adenosine A2B receptor signaling contributes to priapism through HIF-1α mediated reduction of PDE5 gene expression

Prevalence of Deletional Alpha Thalassemia and Sickle Gene in a Tribal Dominated Malaria Endemic Area of Eastern India

AKAP-Dependent Modulation of BCAM/Lu Adhesion on Normal and Sickle Cell Disease RBCs Revealed by Force Nanoscopy

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